As a cutting-edge technology in the field of high-end manufacturing, 3D five-axis laser cutting relies on the coordinated linkage of three linear axes (X/Y/Z) and two rotating axes (A/C) to break the dimensional limitations of traditional three-axis cutting, realizing high-precision and dead-angle-free processing of complex 3D curved surfaces and special-shaped structural workpieces. Based on the in-depth integration of optical engineering, mechanical dynamics and digital control technology, we have summarized and refined six core application processes, which run through the entire process of high-end manufacturing. From precision forming to efficiency improvement, from flexible production to quality assurance, they comprehensively solve the pain points of complex workpiece processing, empower multiple industries such as aerospace, automobile manufacturing and high-end equipment to achieve technological upgrading, and highlight the core barriers and industrial value of laser processing.